Journal article

Strategies to improve antimicrobial utilization with a special focus on developing countries


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Publication Details

Author list: Brian Godman 1,2,3,* , Abiodun Egwuenu 4
, Mainul Haque 5
, Oliver Ombeva Malande 6,7, Natalie Schellack 8
,
Santosh Kumar 9
, Zikria Saleem 10 , Jacqueline Sneddon 11, Iris Hoxha 12, Salequl Islam 13, Julius Mwita 14
,
Renata Cristina Rezende Macedo do Nascimento 15 , Isabella Piassi Dias Godói
16,17 , Loveline Lum Niba 18,19
,
Adefolarin A. Amu 20, Joseph Acolatse 21 , Robert Incoom 21, Israel Abebrese Sefah 22,23 , Sylvia Opanga 24
,
Amanj Kurdi 1,25 , Ibrahim Chikowe 26 , Felix Khuluza 26, Dan Kibuule 27 , Olayinka O. Ogunleye 28,29
,
Adesola Olalekan 30,31 , Vanda Markovic-Pekovic 32, Johanna C. Meyer 2
, Abubakr Alfadl 33,34
,
Thuy Nguyen Thi Phuong 35, Aubrey C. Kalungia 36, Stephen Campbell 37,38, Alice Pisana 39, Janney Wale 40
and R. Andrew Seaton 11,41,42

Publication year: 2021

Journal: Life

Volume number: 11

Issue number: 6

Start page: 528

End page: 573

Number of pages: 46

eISSN: 2075-1729



Antimicrobial resistance (AMR) is a high priority across countries as it increases morbidity, mortality and costs. Concerns with AMR have resulted in multiple initiatives internationally, nationally and regionally to enhance appropriate antibiotic utilization across sectors to reduce AMR, with the overuse of antibiotics exacerbated by the COVID-19 pandemic. Effectively tackling AMR is crucial for all countries. Principally a narrative review of ongoing activities across sectors was undertaken to improve antimicrobial use and address issues with vaccines including COVID-19. Point prevalence surveys have been successful in hospitals to identify areas for quality improvement programs, principally centering on antimicrobial stewardship programs. These include reducing prolonged antibiotic use to prevent surgical site infections. Multiple activities centering on education have been successful in reducing inappropriate prescribing and dispensing of antimicrobials in ambulatory care for essentially viral infections such as acute respiratory infections. It is imperative to develop new quality indicators for ambulatory care given current concerns, and instigate programs with clear public health messaging to reduce misinformation, essential for pandemics. Regular access to effective treatments is needed to reduce resistance to treatments for HIV, malaria and tuberculosis. Key stakeholder groups can instigate multiple initiatives to reduce AMR. These need to be followed up


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Last updated on 2025-06-11 at 12:23