Journal article

Current co-morbidities burden in patients living with HIV in low- and middle-income countries.

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Publication Details

Author list: Mosepele Mosepele

Publication year: 2021

Journal: Current Opinion in HIV AIDS

Journal acronym: Curr Opin HIV AIDS

Volume number: 16

Issue number: 3

ISSN: 1746-630X

eISSN: 1746-6318



Purpose of review

The present review aims to decipher common co-morbidities faced by people living with HIV in low- to middle-income countries, and in particular the sub-Saharan region, which hosts the majority of the HIV burden worldwide.

Recent findings

Well-controlled chronic HIV disease is strongly associated with an increased risk of developing cardiovascular disease. This is partly due to the natural aging process, however recent studies show that using antiretroviral therapy as well as the HIV disease itself may be predisposing factors to the development of cardiovascular diseases, creating a new burden for healthcare facilities in the region. Furthermore, newly completed studies assessing inflammation marker albuminuria and age-related syndrome frailty have been found in a higher prevalence than in non-HIV infected people, with increased morbidity and mortality.

Summary

As antiretroviral medication continues to be well supplied in the region and well tolerated by patients living with HIV, this group is now reckoning with cardiovascular ailments faced by all ageing population therefore there is a need for cardiovascular care systems to be better integrated within the existing, well-performing HIV care systems to address this burden.


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Last updated on 2026-03-02 at 13:54