Journal article

Erysacleuxins C and D, new isoflavones from the twigs of Erythrina sacleuxii Hua and their cytotoxic activity


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Author list: Ombito Japheth O., Bojase Gomotsang, Majinda Runner R. T., Masesane Ishmael B., Schueffler Anja, Opatz Till

Publication year: 2020

Journal name in source: ARABIAN JOURNAL OF CHEMISTRY

Volume number: 13

Issue number: 2

Start page: 4019

End page: 4023

Number of pages: 5

ISSN: 1878-5352

URL: https://www.sciencedirect.com/science/article/pii/S187853521930053X

Languages: English



Two previously undescribed isoflavones, erysacleuxin C (1) and erysacleuxin D (2), together with seven known compounds (3–9), were isolated and identified from the EtOAc extract of the twigs of Erythrina sacleuxii Hua (Leguminosae). The structures of the isolated compounds were determined on the basis of their spectroscopic and spectrometric data. Evaluation of their cytotoxicity against the human cancer HeLa-S3 cell lines indicated IC50 values of 130.4, 54.9 and 73.9 µM for erysacleuxin C (1), erysacleuxin D (2) and butin (9), respectively.


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Last updated on 2022-29-11 at 11:34