Journal article
Potential role of Lu/BCAM in HIV-related atherosclerosis. Afr J Lab Medicine 2019 ISSN
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Publication Details Author list: Motswaledi MS, Kasvosve I, Oguntibeju OO. . Publisher: AOSIS Publishing Publication year: 2019 Journal: African Journal of Laboratory Medicine Volume number: 8 Issue number: 1 ISSN: 2225-2002 eISSN: 2225-2010 |
Atheromatous lesions are formed by macrophages and low-density lipoprotein cholesterol invading the vascular intima. Here we show that increasing cholesterol levels are associated with peripheral monocyte depletion and this imbalance is aggravated by carriage of Lu/BCAM leukocyte adhesion molecules. This is true only in HIV infection and probably explains the risk of atherosclerosis observed in HIV-positive patients. Keywords: cholesterol; Non-high-density lipoprotein cholesterol; Lu/BCAM; Atherosclerosis
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