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Impact of natural selection on global patterns of genetic variation, and association with clinical phenotypes, at genes involved in SARS-CoV-2 infection.


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Author list: Zhang, Verma, Feng, Melo, McQuillan, Hansen, Lucas, Park, Ranciaro, Thompson, Rubel, Campbell, Beggs, Hirbo, Mpoloka, Mokone, Jones, Nyambo, Meskel, Belay, Fokunang, Njamnshi, Omar, Williams, Rader, Ritchie, de la Fuente, Sirugo, Tishkoff

Publication year: 2021

Journal name in source: Research square

Journal acronym: Res Sq

URL: https://pubmed.ncbi.nlm.nih.gov/35580180/

Languages: English



, we identified 13 amino acid changes that are adaptive and specific to the human lineage. Genetic variants that are targets of natural selection are associated with clinical phenotypes common in patients with COVID-19.


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Last updated on 2022-29-11 at 11:33