Book chapter abstract

Comparative Review of the Synthesis of Flavanones via the Reaction of Cinnamic Acids and Phenols and the Reaction of 2-Hydroxyacetophenones and Benzaldehydes


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Author list: Ishmael B. Masesane, Kenamile Rabasimane, Kibrom G. Bedane

Publication year: 2018

URL: https://www.springerprofessional.de/en/comparative-review-of-the-synthesis-of-flavanones-via-the-reacti/15124488

Languages: English



AbstractThis review compares the efficiency of a three-step procedure developed by the authors for the synthesis of flavanones that relied on the boron trifluoride diethyl etherate (BF3·OEt2)-mediated reaction of cinnamic acid and phenols to the one-step or two-step procedures reported in literature involving the reaction of 2-hydroxyacetophenones and benzaldehydes. The three-step procedure was found to give the flavanones in comparable yields to both the one-step and the two-step literature methods.


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Last updated on 2022-29-11 at 11:34