Journal article

Potential role of Lu/BCAM in HIV-related atherosclerosis.


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Publication Details

Author list: Motswaledi MS, Kasvosve I, Oguntibeju OO

Publisher: AOSIS Publishing

Publication year: 2019

Journal: African Journal of Laboratory Medicine

Volume number: 8

Issue number: 1

ISSN: 2225-2002

eISSN: 2225-2010



Atheromatous lesions are formed by macrophages and low-density lipoprotein cholesterol invading the vascular intima. Here we show that increasing cholesterol levels are associated with peripheral monocyte depletion and this imbalance is aggravated by carriage of Lu/BCAM leukocyte adhesion molecules. This is true only in HIV infection and probably explains the risk of atherosclerosis observed in HIV-positive patients.


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Last updated on 2024-10-10 at 12:45