Conference proceedings article

ZnO nanowire-FET for charge-based sensing of protein biomolecules


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Author list: N.M.J. Ditshego, 1N.A.B. Ghazali, M. Ebert, K. Sun, I. Zeimpekis, P. Ashburn, M.R.R. de Planque, H.M.H. Chong

Publication year: 2015

Title of series: 2015 IEEE 15th International Conference on Nanotechnology (IEEE-NANO 2015)

Number in series: 15

Start page: 801

End page: 804

Number of pages: 4



Top-down method was used to fabricate zinc oxide (ZnO) nanowire field effect transistor (NWFET) biosensor. The nanosensor was used to measure the electrical characteristics of lysozyme (LYSO) and bovine serum albumin (BSA) protein solutions in phosphate buffered saline (PBS). The LYSO and BSA proteins are oppositely charged at measurement pH of 7.4. Subthreshold voltage shift of 340 mV and 700 mV due to surface charge effect on the device channel is obtained for the LYSO and BSA solutions respectively. A NWFET sensitivity of 72 % is achieved for the LYSO proteins while the BSA proteins resulted in a sensitivity of 98%.


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Last updated on 2024-21-11 at 15:42